Thermo Fisher Scientific Glucagon Polyclonal Antibody
Thermo Fisher Scientific의 Glucagon Polyclonal Antibody는 인간 및 생쥐 반응성을 가진 토끼 IgG 항체로, Western blot, IHC, Flow cytometry에 적합합니다. KLH 결합 합성 펩타이드(25-54 aa)로 면역원 제작, 2 mg/mL 농도의 액상 형태로 제공되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 25–54 amino acids from the N-terminal region of human GCG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2107206 |
Target Information
Glucagon is a 29-residue polypeptide hormone (MW 3482) produced in the pancreas. A related hormone, enteroglucagon (or oxyntomodulin), produced in the intestinal mucosa, extends the glucagon sequence by 8 additional residues at the C-terminus. Glucagon promotes glycogenolysis, lipolysis, gluconeogenesis, and ketogenesis—actions opposing insulin, thus increasing blood glucose levels. Immunocytochemical studies show glucagon localized in pancreatic alpha cells, comprising 15–20% of islet cells, mainly at the periphery. Glucagon-type peptides are associated with tumors or glucagonomas, with no known deficiency or hyperplasia states. Glucagon-specific antibodies are valuable as cell and tumor markers and for hormone quantification in research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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