Thermo Fisher Scientific SUPT4H1 Monoclonal Antibody (OTI5F12), TrueMAB
SUPT4H1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 최적화됨. 인간 단백질에 반응하며, 액상 형태로 제공. PBS/BSA/glycerol 버퍼에 보존되고, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F12 |
| Immunogen | Full length human recombinant protein of human SUPT4H1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.
DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.
It cooperates with the NELF complex to enhance transcriptional pausing near promoters, facilitating assembly of elongation-competent RNA polymerase II complexes.
DSIF and NELF inhibit TFIIS/S-II to promote pausing, while DSIF also positively regulates elongation and is required for activation by HIV-1 Tat.
DSIF suppresses transcriptional pausing and prevents premature release of HIV-1 transcripts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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