Thermo Fisher Scientific ARS2 Polyclonal Antibody
ARS2 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, Human/Mouse/Rat 반응성. Protein A 정제, 고농도(1 mg/mL) 액상 형태로 안정적 저장 가능.
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Thermo Fisher Scientific ARS2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ARS2, amino acids 721–800 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the processing complex containing DGCR8 and DROSHA, playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA) via interaction with NCBP1/CBP80 of the CBC complex. Involved in S-phase cell cycle progression. Modulates arsenic sensitivity rather than conferring arsenite resistance. Independently promotes neural stem cell self-renewal by binding the SOX2 promoter and activating its transcription. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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