Thermo Fisher Scientific MALT1 Monoclonal Antibody (OTI1B12), TrueMAB
인간 MALT1 단백질을 인식하는 단일클론 항체로 Western blot에 적합합니다. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용했습니다. 무보존제, 동결건조 형태이며 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B12 |
| Immunogen | Full length human recombinant MALT1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MALT1 (Paracaspase) is a caspase-like protein identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000).
It contains:
- N-terminal death domain
- Two Ig-like domains
- C-terminal caspase-like domain
MALT1 binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB signaling.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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