Thermo Fisher Scientific NAE1 Polyclonal Antibody
Thermo Fisher Scientific의 NAE1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상형 항체로, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NAE1. Recombinant protein control fragment (Product #RP-98683) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644435 |
Product Specific Information
Immunogen sequence:
KPFPELREHF QSYDLDHMEK KDHSHTPWIV IIAKYLAQWY SETNGRIPKT YKEKEDFRDL IRQGILKNEN GAPEDEENFE EAIKNVNTAL NTTQIPSSIE DIFNDDR
Antigen sequence identity:
- Mouse: 97%
- Rat: 98%
Target Information
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties and is thought to play a role in the pathogenesis of Alzheimer’s disease.
Additionally, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein.
This protein is required for cell cycle progression through the S/M checkpoint.
Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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