Thermo Fisher Scientific Filensin Polyclonal Antibody
Human Filensin 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며, 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:5,000–1:10,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Filensin (UniProt ID: Q12934-1, antigen range: 407–508) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641641 |
Product Specific Information
Immunogen sequence:
ESESKFESES KEVSPLTQEG APEDVPDGGQ ISKGFGKLYR KVKEKVRSPK EPETPTELYT KERHVLVTGD ANYVDPRFYV SSITAKGGVA VSVAEDSVLY DG
Highest antigen sequence identity to orthologs:
- Mouse: 59%
- Rat: 58%
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are components of the beaded filament (BF), a unique cytoskeletal structure.
Mutations in this gene cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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