Thermo Fisher Scientific PSMD3 Monoclonal Antibody (OTI2A2), TrueMAB
PSMD3 단백질을 인식하는 마우스 단클론 항체로, Western blot과 유세포분석에 적합합니다. HEK293T 세포에서 발현된 full-length human PSMD3를 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A2 |
| Immunogen | Full length human recombinant protein of human PSMD3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two α-rings and two β-rings).
- The 19S regulator includes a base with six ATPase subunits and two non-ATPase subunits, and a lid with up to ten non-ATPase subunits.
Proteasomes are abundant in eukaryotic cells and degrade peptides in an ATP/ubiquitin-dependent manner.
The immunoproteasome variant is essential for processing class I MHC peptides.
The PSMD3 gene encodes one of the non-ATPase subunits of the 19S regulator lid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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