Thermo Fisher Scientific PLCL1 Polyclonal Antibody
Human PLCL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.3 mg/mL 농도의 액상 제품. GABA 수용체 관련 신호 조절 연구에 적합.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLCL1. Recombinant protein control fragment (Product #RP-96032) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645635 |
Product Specific Information
Immunogen sequence:
LRYLVSRSKQ PLDFMEGNQN TPRFMWLKTV FEAADVDGNG IMLEDTSVEL IKQLNPTLKE AKIRLKFKEI QKSKEKLTTR VTEEEF
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 99%
Target Information
PLCL1 is involved in an inositol phospholipid-based intracellular signaling cascade. It shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. It is a component in the phospho-dependent endocytosis process of GABA A receptor and regulates receptor turnover, contributing to GABA-mediated synaptic inhibition. Aberrant expression may contribute to lung carcinoma progression. Acts as an inhibitor of PPP1C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-56879_PLCL1_Q15111-1_Rabbit.svg, PA5-56879_PLCL1_Q15111-1_Rabbit_PDP.jpeg)
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