Thermo Fisher Scientific Phospho-RSK1 (Thr573) Polyclonal Antibody
Human RSK1 단백질의 Thr573 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 다양한 종에서 예측 반응성 확인됨. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human p90 RSK1 (phospho Thr573). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736404 |
Product Specific Information
- Positive Control: A431 whole cell extracts
- Predicted Reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase involved in the MAPK cascade. It controls cellular proliferation and differentiation through phosphorylation of transcription factors. RPS6KA1 contains two nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the MAPK signaling pathway. Its activity is implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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