Thermo Fisher Scientific SCFD1 Monoclonal Antibody (OTI10D10), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The de novo synthesis of pyrimidine nucleotides is essential for mammalian cell proliferation.
This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis:

• Carbamoylphosphate synthetase (CPS II)
• Aspartate transcarbamoylase
• Dihydroorotase

This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, linking MAPK activation to pyrimidine nucleotide biosynthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.