
Thermo Fisher Scientific KCNK3 Monoclonal Antibody (N374/48)
KCNK3 단백질을 검출하는 Mouse 모노클로날 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF에 적합하며 TASK1 채널에 특이적입니다. Unconjugated 형이며, 고순도 Protein G 정제 및 안정한 PBS/glycerol buffer로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N374/48 |
| Immunogen | Fusion protein amino acids 251–411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). <30% identity with TASK3. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.1% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2735241 |
Additional Formats
- APC (MA5-45701)
- FITC (MA5-45702)
- PE (MA5-45704)
- PerCP (MA5-45703)
- Request custom conjugation
Product Specific Information
1 µg/mL of MA5-27677 was sufficient for detection of TASK1 Potassium Channel in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 50 kDa. Does not cross-react with TASK3.
This antibody was formerly sold as clone S374-48.
Target Information
KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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