Thermo Fisher Scientific Folate Binding Protein Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

Anti-FOLATE BINDING PROTEIN is an IgG fraction antibody purified from monospecific antiserum by a multi-step process including delipidation, salt fractionation, and ion-exchange chromatography followed by extensive dialysis.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Folate Binding Protein (Bovine Milk).
Cross-reactivity against Folate Binding Protein from other tissues and species may occur but has not been specifically determined.

Target Information

The protein encoded by this gene is a member of the folate receptor family. Members of this family bind folic acid and its reduced derivatives and transport 5-methyltetrahydrofolate into cells.
This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form.
Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency.
Multiple transcript variants encoding the same protein have been identified due to the presence of two promoters, multiple transcription start sites, and alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.