
Thermo Fisher Scientific SMARCC2/BAF170 Polyclonal Antibody
SMARCC2/BAF170 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, IP 등 다양한 응용에 적합. 인간 및 생쥐 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 4°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1164 and the C-terminus (residue 1214) of Human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (BRG1-associated factor 170) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
Cdc73 is a tumor suppressor likely involved in transcriptional and post-transcriptional control pathways. It is part of the PAF1 complex, composed of Paf1, Cdc73, Leo1, Rtf1, and Ctr9. The PAF1 complex associates with RNA polymerase II and functions in transcription elongation, coordinating histone modifications linked to active transcription. Additionally, it plays a role in RNA quality control and may influence cell cycle progression through regulation of cyclin D1/PRAD1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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