Thermo Fisher Scientific CD14 Monoclonal Antibody (TuK4), APC-Alexa Fluor 750
인간 CD14 단백질을 인식하는 TuK4 클론의 마우스 모노클론 항체로, APC-Alexa Fluor 750 형광 표지로 다중 컬러 유세포 분석에 적합함. 고순도 정제된 액상 형태이며, 4°C에서 암소 보관. 다양한 형광 표지 형식으로도 제공.
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Thermo Fisher Scientific CD14 Monoclonal Antibody (TuK4), APC-Alexa Fluor 750
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-dependent
Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TuK4 |
| Immunogen | Human CD14 |
| Conjugate | APC-Alexa Fluor™ 750 |
| Excitation / Emission Max | 756 / 785 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with BSA, 10% sucrose |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10373536 |
Available Formats
- Unconjugated
- Alexa Fluor 647
- Alexa Fluor 700
- APC
- Biotin
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Cyanine5.5
- PE-Texas Red
- PerCP
- Qdot 655
- Qdot 705
- Qdot 800
- TRI-COLOR
- Request custom conjugation
Product Specific Information
The allophycocyanin (APC)-Alexa Fluor™ 750 dye tandem conjugate allows for multicolor measurements using excitation by lasers that emit from 633 to 650 nm.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils. It functions as a lipopolysaccharide (LPS) receptor and is released into serum as both secreted and cleaved GPI-anchored forms. CD14 interacts with LPS via LBP (lipopolysaccharide-binding protein), aiding in immune response modulation. Soluble CD14 (sCD14) can distinguish structural differences between LPS molecules and plays a role in neutralizing foreign lipopolysaccharides. It also binds apoptotic cells and influences allergic, inflammatory, and infectious processes. Alternative splicing produces multiple transcript variants encoding the same CD14 isoform. CD14 dysfunction is associated with mycobacterium chelonae infection and croup.
Classification
Analyte Specific Reagent
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