Thermo Fisher Scientific CRISP2 Polyclonal Antibody
Human CRISP2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol 포함. 남성 생식 관련 단백질 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CRISP2. Recombinant protein control fragment (Product #RP-94742) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790343 |
Product Specific Information
Immunogen sequence:
GCPDDCDKGL CTNSCQYQDL LSNCDSLKNT AGCEHELLKE KCKATCLCEN
Target Information
The cysteine-rich secretory proteins (CRISP) family consists of four proteins highly expressed in the male reproductive tract, associated with roles in male fertility.
CRISP2 (also known as TPX1) is involved in adhesion between spermatids and Sertoli cells, and together with CRISP1, may participate in sperm-egg fusion.
CRISP2 regulates Ca²⁺ influx through ryanodine receptors (RYR), influencing acrosome reaction or sperm motility.
It binds to MAP3K11 and localizes to the developing acrosome, suggesting the CRISP2–MAP3K11 complex may play a role in acrosome development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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