Thermo Fisher Scientific KChIP2 Monoclonal Antibody (OTI3D8)
KChIP2 단백질을 인식하는 Thermo Fisher의 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료에 반응하며 비결합형 액상 항체 형태로 제공. 심장 및 신경계 연구용으로 적합하며, -20°C에서 보관.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D8 |
| Immunogen | Full length human recombinant protein of KCNIP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724551 |
Target Information
Voltage-gated potassium (Kv) channels are key components of potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain, these channels prevent reverse-propagation of action potentials.
KChIPs (Kv channel interacting proteins) are calcium-binding proteins that associate with Kv4 channels and modulate their function.
There are three known KChIPs:
- KChIP1: Expressed in the brain
- KChIP2: Expressed in the brain, heart, and lung; has three isoforms (a, b, c)
- KChIP3 (Calsenilin / DREAM): Expressed in the brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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