Thermo Fisher Scientific Galectin 12 Polyclonal Antibody
Galectin 12 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성을 가지며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Galectin 12 (LGALS12), amino acids 101–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Galectin-12 (also known as galectin-related inhibitor of proliferation 1 in mouse) is a 314 amino acid protein encoded by the human gene LGALS12. It belongs to the galectin family of β-galactoside-binding proteins with conserved carbohydrate recognition domains. Galectin-12 binds lactose and may be involved in adipocyte apoptosis. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. It is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The gene is expressed in mouse preadipocytes and is upregulated during cell cycle arrest, coinciding with differentiation competence in response to adipogenic hormone stimulation. Galectin-12 expression is downregulated by insulin resistance–inducing hormones and may play a role in the pathogenesis of insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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