Thermo Fisher Scientific CD19 Monoclonal Antibody (MB19-1), APC, eBioscience
마우스 CD19를 인식하는 MB19-1 단클론 항체로, B 세포 표면 마커 분석에 적합합니다. APC 형광체로 결합되어 유세포분석(Flow Cytometry)에 사용됩니다. 0.2 mg/mL 농도의 액상 형태이며, 4°C에서 암소 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 17-0191-8x (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD19 Monoclonal Antibody (MB19-1), APC, eBioscience
Applications
Tested Application
- Flow Cytometry (Flow)
Tested Dilution
- ≤ 0.5 µg/test
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgA, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MB19-1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_469357 |
Additional Formats
- Biotin
- FITC
- Functional Grade
- PE
- Custom conjugation available upon request
Product Specific Information
The MB19-1 monoclonal antibody reacts with mouse CD19, a 95 kDa transmembrane glycoprotein expressed by B cells during all stages of development except terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together with CD21, CD81, and MHC class II, CD19 forms a multimolecular complex associated with the B cell receptor (BCR). Signaling through CD19 induces tyrosine phosphorylation, calcium flux, and B cell proliferation.
Staining with MB19-1 and its conjugates is typically dimmer than that of the rat anti-mouse CD19 antibody clone 6D5.
Applications Reported: Flow cytometric analysis
Applications Tested: Tested by flow cytometry using mouse splenocytes at ≤ 0.5 µg/test (100 µL final volume). Optimal titer should be determined empirically.
Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on nearly all peripheral B cells and certain myeloid leukemia cells. CD19 acts as a key regulator of normal and malignant B cell proliferation and serves as a signal-amplifying co-receptor for the BCR. Mutations in the CD19 gene can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without authorization.
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