Thermo Fisher Scientific KV4.1 (KCND1) Polyclonal Antibody
Thermo Fisher Scientific의 KV4.1 (KCND1) Polyclonal Antibody는 인간 및 마우스 시료에서 사용 가능한 rabbit IgG 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 71 kDa 단백질을 검출하며, 고순도(>95%)를 제공합니다.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 559–610 of human KV4.1 (KCND1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2554071 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 71 kDa.
Purity is greater than 95% by SDS-PAGE.
Target Information
The KV gene family encodes more than 30 genes that comprise the subunits of K⁺ channels, varying in gating, permeation, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers of pore-forming alpha-subunits (KVα), including KV1, KV2, KV3, and KV4 proteins, along with accessory KVβ subunits that modify gating properties. Differences in trafficking, biosynthetic processing, and surface expression of major KV1 subunits (KV1.1, KV1.2, KV1.4) in rat and human brain suggest highly regulated assembly for functional neuronal channel formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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