Thermo Fisher Scientific CD299 (DC-SIGN/L) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.25 µg/mL

View 1 publication 1 publication

Immunohistochemistry (IHC)

5 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human CLEC4M (aa 51-100). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD299,uniProtId:Q9H2X3-1,ncbiNodeId:9606,antigenRange:51-100,antigenLength:399,antigenImageFileName:PA5-42164_CD299_Q9H2X3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-42164_CD299_Q9H2X3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2605446

Product Specific Information

Peptide sequence: LVLQLLSFML LAGVLVAILV QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV

Sequence homology: Human: 100%; Pig: 86%

Target Information

CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.