Thermo Fisher Scientific Vitronectin Monoclonal Antibody (HV23)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

-

ELISA (ELISA)

1:30,000

-

Product Specifications

Species Reactivity

Bovine, Dog, Horse, Cat, Goat, Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

HV23

Immunogen

Human vitronectin purified from plasma by heparin-affinity chromatography. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Vitronectin,uniProtId:P04004-1,ncbiNodeId:9606,antigenRange:1-478,antigenLength:478,antigenImageFileName:CSI_003-23-02_Vitronectin_P04004-1_House_mouse.svg,antigenImageFileNamePDP:CSI_003-23-02_Vitronectin_P04004-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.05 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1088275

Product Specific Information

CSI 003-23-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 003-23-02 cross-reacts with vitronectin from cat, dog, goat, cow and to a lesser extent with horse.

CSI 003-23-02 has been successfully used in ELISA and Western blotting techniques. By Western blot, CSI 003-23-02 detects a band of 65-75 kDa representing vitronectin.

Epitope of CSI 003-23-02 is located in the somatomedin B domain, but differs from that of CSI 003-01-02.

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Target Information

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.