Thermo Fisher Scientific MICAL2 Polyclonal Antibody
인간 MICAL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 적합합니다. KLH 접합 합성 펩타이드(55–83 aa, N-말단)를 면역원으로 사용하였으며, 2.0 mg/mL 농도의 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 55–83 amino acids from the N-terminal region of human MICAL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2544102 |
Target Information
MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. There are three known isoforms: MICAL1, MICAL2, and MICAL3, as well as MICAL-like proteins MICAL-L1 and MICAL-L2.
MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain, and a Lin11, Isl-1, and Mec-3 (LIM) domain.
It has been demonstrated that MICAL2 regulates actin stress fibers and is required for normal actin organization. Additionally, a novel splicing variant, MICAL2-PV, has been reported to be involved in prostate cancer progression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-26602_MICAL2_O94851-7_Rabbit.svg
- PA5-26602_MICAL2_O94851-7_Rabbit_PDP.jpeg
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