Thermo Fisher Scientific TGFBR3 Polyclonal Antibody
Human TGFBR3 단백질에 특이적인 Rabbit Polyclonal Antibody로 IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS, 40% glycerol 버퍼에 보관. 암 연구 및 TGF-β 신호전달 관련 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TGFBR3. Recombinant protein control fragment (Product #RP-88952). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789502 |
Product Specific Information
Immunogen sequence:
GYSGMDVTLL DPTCKAKMNG THFVLESPLN GCGTRPRWSA LDGVVYYNSI VIQVPALGDS SGWPDGYEDL ESGDNGFPGD MDEGDASLFT RPEIVVFNCS LQQVRNPSSF QEQPHGNITF NMELYNTDLF
Target Information
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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