Thermo Fisher Scientific alpha-2c Adrenergic Receptor Polyclonal Antibody
Rabbit polyclonal antibody recognizing human alpha-2c adrenergic receptor. Validated for IHC (Paraffin) at 26 µg/mL. High specificity via antigen affinity purification. Supplied as liquid, unconjugated form for research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 26 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminal extracellular domain of human ADRA2C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550713 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey (100%)
Dog (89%)
Rat, Guinea pig (83%)
Target Information
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily, including three highly homologous subtypes: alpha2A, alpha2B, and alpha2C.
These receptors regulate neurotransmitter release from sympathetic nerves and adrenergic neurons in the central nervous system.
Studies in mice indicate both alpha2A and alpha2C subtypes are essential for normal presynaptic control of transmitter release.
The alpha2A subtype inhibits release at high stimulation frequencies, while the alpha2C subtype modulates neurotransmission at lower levels of nerve activity.
This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-33330_alpha-2c_Adrenergic_Receptor_P18825-1_Rabbit.svg
- PA5-33330_alpha-2c_Adrenergic_Receptor_P18825-1_Rabbit_PDP.jpeg
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