Thermo Fisher Scientific Angiomotin Polyclonal Antibody
Rabbit polyclonal antibody targeting Angiomotin (AMOT) for research use. Unconjugated liquid form with 0.20 µg/mL concentration. Stored at 4°C and shipped on wet ice. Predicted cross-reactivity with Mouse based on sequence identity.
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Thermo Fisher Scientific Angiomotin Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 750–800 of AMOT (UniProt ID: Q4VCS5-1, antigen length: 1084) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 µg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
AMOT (Angiomotin) belongs to the motin family of angiostatin-binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs.
It plays a central role in tight junction maintenance via the complex formed with ARHGAP17, regulating the uptake of polarity proteins at tight junctions.
AMOT is predominantly expressed in endothelial cells of capillaries and larger vessels of the placenta, where it may mediate the inhibitory effect of angiostatin on tube formation and migration of endothelial cells toward growth factors during angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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