Thermo Fisher Scientific SSB Monoclonal Antibody (OTI6G7), TrueMAB
SSB 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, IP에 사용 가능. Human 및 Dog 반응성. Lyophilized 형태로 제공되며, PBS buffer에 8% trehalose 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G7 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human SSB expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
La (SSB) protein is involved in various RNA metabolic processes, including:
- Binding and protecting 3′ UUU(OH) elements of newly RNA polymerase III-transcribed RNA
- Processing 5′ and 3′ ends of pre-tRNA precursors
- Acting as an RNA chaperone
- Binding viral RNAs associated with hepatitis C virus
La protein was originally characterized by its reactivity with autoantibodies from patients with Sjögren syndrome and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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