Thermo Fisher Scientific PTGES2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTGES2 for WB and IHC applications. Recognizes recombinant PTGES2 with high specificity. Suitable for research use in inflammation and prostaglandin biosynthesis studies. Provided in liquid form with PBS/glyce...
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PTGES2. Recombinant protein control fragment (Product #RP-104567) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664793 |
Product Specific Information
Immunogen sequence:
AQDLHAERSAA QLSLSSRLQL TLYQYKTCPF CSKVRAFLDF HALPYQVVEV NPVRRAEIKF SSYRKVPILV AQEGESSQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 91%
Target Information
The PTGES2 gene encodes the enzyme prostaglandin E synthase 2 (PTGES2), which is essential for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. This enzyme functions downstream of the cyclooxygenase (COX) pathway, interacting with COX-1 and COX-2. PTGES2 plays a key role in inflammation, fever generation, and pain processes. It is a membrane-associated protein distinct from other prostaglandin synthases due to its specific regulatory properties. PTGES2 activity fine-tunes PGE2 levels in tissues, influencing immune and vascular signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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