Thermo Fisher Scientific RBP4/Retinol Binding Protein 4 Monoclonal Antibody (RBP4, 4041)
인간 RBP4 단백질을 인식하는 단클론 항체로 면역조직화학(IHC) 및 펩타이드 어레이 분석에 적합합니다. 비결합형 액상 형태이며 Protein A/G로 정제되었습니다. 200 µg/mL 농도로 제공되며 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RBP4, 4041 |
| Immunogen | Recombinant fragment (around aa29–148) of human RBP4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature (RT).
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 minutes.
Target Information
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood.
It delivers retinol from liver stores to peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, preventing loss by filtration through kidney glomeruli.
Vitamin A deficiency blocks secretion of the binding protein post-translationally, resulting in defective delivery and supply to epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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