Thermo Fisher Scientific PADI2 Polyclonal Antibody
PADI2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A 정제 및 고순도 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PADI2 (amino acids 42–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PADI2 gene encodes a member of the peptidyl arginine deiminase (PAD) enzyme family, which catalyzes the post-translational deimination of proteins, converting arginine residues into citrullines in the presence of calcium ions. PAD family members display distinct substrate specificities and tissue-specific expression patterns. The type II enzyme (PADI2) is the most widely expressed, with known substrates including myelin basic protein (CNS) and vimentin (skeletal muscle, macrophages). PADI2 is implicated in neurodegenerative diseases such as Alzheimer’s disease and multiple sclerosis, and also in glaucoma pathogenesis. This gene is part of a cluster with four other paralogous PAD genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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