Thermo Fisher Scientific CABLES1 Polyclonal Antibody
Human CABLES1 단백질에 특이적인 Rabbit Polyclonal Antibody. ICC/IF에 사용 가능하며, 0.25–2 µg/mL 농도로 권장. 항원 친화 크로마토그래피로 정제된 액상 제품으로, PBS(40% glycerol) 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CABLES1. Recombinant protein control fragment (Product # RP-108619) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792082 |
Product Specific Information
Immunogen sequence:
SRGRLNSFTQ GILPIAFSRP TSQNYCSLEQ PGQGGSTSAF EQLQRSRRRL ISQRSSLETL EDIEENAPLR RCRTLSGSPR PKN
Target Information
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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