Thermo Fisher Scientific CABLES1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CABLES1. Recombinant protein control fragment (Product #RP-108619). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CABLES1,uniProtId:Q8TDN4-1,ncbiNodeId:9606,antigenRange:236-318,antigenLength:633,antigenImageFileName:PA5-84933_CABLES1_Q8TDN4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84933_CABLES1_Q8TDN4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2792082

Product Specific Information

Immunogen sequence: SRGRLNSFTQ GILPIAFSRP TSQNYCSLEQ PGQGGSTSAF EQLQRSRRRL ISQRSSLETL EDIEENAPLR RCRTLSGSPR PKN

Target Information

Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.