
Thermo Fisher Scientific CTDSPL Polyclonal Antibody
CTDSPL 단백질을 타깃으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Flow cytometry에 적합하며, 고순도 Protein A 및 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific CTDSPL Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Flow Cytometry (Flow): 1:10–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–30 amino acids from the N-terminal region of human CTDSPL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541046 |
Target Information
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Preferentially catalyzes the dephosphorylation of Ser-5 within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.
Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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