Thermo Fisher Scientific APC11 Polyclonal Antibody
Human Apc11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 적합. 고순도 항원 친화 크로마토그래피로 정제되었으며, 다양한 종에서 예측 반응성 보유. 연구용으로만 사용 가능.
- 카탈로그번호
- PA529148
- 판매단위
- pk
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Thermo Fisher Scientific APC11 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 26–84 of Human Apc11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546624 |
Product Specific Information
- Recommended positive controls: 293T, H1299, HeLaS3, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Together with the cullin protein ANAPC2, Apc11 constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
The APC/C complex mediates ubiquitination and degradation of target proteins, mainly forming Lys-11-linked polyubiquitin chains and, to a lesser extent, Lys-48 and Lys-63 chains.
May recruit E2 ubiquitin-conjugating enzymes to the complex. [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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