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Thermo Fisher Scientific Human Furin Recombinant Protein

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인간 유래 Furin Recombinant Protein으로 효소 활성 검증된 연구용 시약. 비인간 영장류 세포에서 발현되며, 다양한 효소 반응 및 단백질 절단 연구에 활용 가능. 고순도 액상 형태로 -80°C에서 안정 보관.

카탈로그번호: RP062
브랜드: Thermo Fisher Scientific
카테고리: Enzymes
판매단위: pk

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마지막 업데이트 2025. 08. 04. 오전 05:58

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Thermo Fisher Scientific RP062 Human Furin Recombinant Protein 50 ul pk판매 단위 pk

재고 1개재고 1개

708,700원VAT 포함 779,570원

재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific Human Furin Recombinant Protein

Applications

Product Specifications

항목	내용
Species	Human
Published Species	Human
Expression System	Non-Human Primate cells
Amino Acid Sequence	Human Furin convertase protein, amino acids 1–713
Class	Recombinant
Type	Protein
Activity	Specific Activity = 1 U/µL; 1 U = amount of furin releasing 1 pmol of AMC from pERTKR-MCA in 1 min
Conjugate	Unconjugated
Form	Liquid
Purification	Purified
Storage Buffer	0.02M Bis-tris with 1mg/mL BSA
Contains	No preservative
Storage Conditions	-80°C, Avoid Freeze/Thaw Cycles
Shipping Conditions	Dry ice

Product Specific Information

RP-062 has an activity of 1 U/µL, where one unit (1 U) is defined as the amount of furin that can release 1 pmol of AMC from the fluorogenic peptide pERTKR-MCA in one minute.
As a fully functional enzyme, RP-062 can be used in various enzymatic assays.
This furin construct represents amino acid residues 1–713 from human furin convertase protein.

Target Information

Furin is a membrane-associated, calcium-dependent serine protease belonging to the subtilisin-like prohormone convertase (PC) family. These enzymes cleave most prohormones and neuropeptide precursors, as well as numerous cellular, viral, and bacterial proteins transported via the secretory pathway.

Furin and other PC family members share structural features:

~10 kDa amino-terminal proregion
~55 kDa conserved subtilisin-like catalytic domain
Variable carboxyl-terminal domain

Activation occurs following proregion cleavage in the appropriate cellular compartment.
Furin is the only known PC possessing a transmembrane domain.
Cleavage of target proteins occurs at the carboxyl-terminus of the consensus sequence RX(K/R)R.
The acidic peptide sequence C771PSDSEEDEG780 localizes furin to the trans-Golgi network, and phosphorylation of serine residues in this region modulates intracellular routing.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.