Thermo Fisher Scientific Polysialic acid Chimeric Recombinant Rabbit Monoclonal Antibody (735)
Polysialic acid(PSA)를 특이적으로 인식하는 재조합 토끼 단클론 항체입니다. Western blot, IHC, Flow cytometry, IP 등 다양한 응용에 사용 가능합니다. 인간, 마우스, 랫트 시료에 반응하며 HEK293 세포에서 발현되었습니다. 단백질 A로 정제된 액상 항체로 연구용에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 3 µg/mL | |
| Flow Cytometry (Flow) | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 735 |
| Immunogen | Homopolymers of alpha-2,8-linked sialic acid of Escherichia coli K1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074300 |
Product Specific Information
Specificity: Recognizes Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of alpha-2,8-linked sialic acid of Escherichia coli K1.
Target Information
Polysialic acid is a glycan polymer composed of repeating units of the monosaccharide sialic acid. It consists of a linear chain of alpha-2,8-linked sialic acid residues that can extend up to 200 units in length. This negatively charged molecule is commonly present in the cell membranes of various organisms, including bacteria and animals, and plays a crucial role in regulating cell adhesion, migration, and neural development. Polysialic acid is also being explored for its potential therapeutic applications in the treatment of certain cancers and neurological disorders.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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