
Thermo Fisher Scientific Protein APC Recombinant Superclonal Antibody (1HCLC)
Human APC 단백질(aa 2-310)에 특이적인 Recombinant Superclonal Rabbit IgG 항체로, 높은 감도와 일관성을 제공. ICC/IF에 2 µg/mL로 사용 가능하며, Protein A로 정제됨. PBS(pH 7.2) 버퍼와 sodium azide 함유, 4°C 단기 또는 -20°C 장기 보관 권장.
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Thermo Fisher Scientific Protein APC Recombinant Superclonal Antibody (1HCLC)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 1HCLC |
| Immunogen | Protein corresponding to Human APC (aa 2–310) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633099 |
Product Specific Information
This antibody is predicted to react with Monkey, Cat, Pig, and Bovine.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing both the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency of recombinant production.
These antibodies recognize multiple epitope sites on the target and provide higher detection sensitivity for low abundance targets. Each lot contains a known mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability associated with polyclonal antibody production.
Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
The APC gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is involved in processes such as cell migration, adhesion, transcriptional activation, and apoptosis.
Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that typically progresses to malignancy. Disease-associated mutations are often clustered in the mutation cluster region (MCR), leading to truncated protein products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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