Thermo Fisher Scientific IL6R VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1278)
IL6R 표적 Alpaca 유래 재조합 단일클론 항체로, ELISA, Flow Cytometry, SPR 등 다양한 분석에 적합합니다. CHO 세포에서 발현되며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 인간 IL6R 반응성이 있으며, 금속 킬레이트 크로마토그래피로 정제되었습니다.
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Thermo Fisher Scientific IL6R VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1278)
Applications and Tested Dilution
- Flow Cytometry (Flow): Assay-dependent
- ELISA: Assay-dependent
- Surface Plasmon Resonance (SPR): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1278 |
| Immunogen | Recombinant Human CD126 / IL6R / IL-6RA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor.
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex.
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response.
The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines.
Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases, and prostate cancer.
Alternatively spliced transcript variants encoding distinct isoforms have been reported.
A pseudogene of this gene is found on chromosome 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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