Thermo Fisher Scientific BMP-2 Polyclonal Antibody
BMP-2 단백질을 인식하는 염소 유래 폴리클로날 항체로, 인간 시료에 반응하며 ICC/IF에 적합합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, 아지드 보존제를 포함합니다. 골형성 관련 연구 및 BMP-2 신호 경로 분석에 유용합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence QRKRLKSSCKRHP (aa 288–300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933583 |
Product Specific Information
- This antibody is expected to recognize the N terminus of the mature BMP-2 protein.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Bone Morphogenic Proteins (BMPs) are members of the TGF-beta superfamily that regulate bone and cartilage formation. Mature BMPs (30–38 kDa) form a cysteine knot structure similar to TGF-beta. Lovostatin enhances bone formation by activating the bmp-2 gene. BMPs induce bone matrix protein production and modulate stromal cell and osteoclast proliferation. They also play roles in visceral development, cell differentiation, apoptosis, and morphogenesis. BMPs contribute to dorsal/ventral patterning and signal via Smad proteins through type I and II receptor interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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