Thermo Fisher Scientific CSMD1 Polyclonal Antibody
CSMD1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 및 마우스 시료에 반응합니다. IHC(P)에서 1:50–1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 종양 억제 및 면역 관련 연구에 적합합니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human CUB and Sushi multiple domains 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636098 |
Product Specific Information
This antibody detects endogenous levels of total CSMD1 protein.
Target Information
CSMD1 (CUB and Sushi multiple domains 1) is a human protein encoded by the CSMD1 gene. It is a potential tumor suppressor, and its deletion may result in more aggressive behavior of head and neck carcinomas.
CSMD1 is part of the complement system, functioning in both the classical and alternative pathways to defend against pathogens. It is primarily located in nerve growth cones, where it blocks the classical immune pathway and contributes to tumor suppression. Mutations in CSMD1 are associated with squamous cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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