Thermo Fisher Scientific Calcium Channel beta-4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive control: HeLa cells
• Predicted reactivity: Mouse (99%), Rat (99%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
The encoded protein modulates G protein inhibition, increases peak calcium current, controls alpha-1 subunit membrane targeting, and shifts the voltage dependence of activation and inactivation.
Mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy. Multiple transcript variants encoding different isoforms have been identified.

⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.