Thermo Fisher Scientific BAK Polyclonal Antibody
Human BAK 단백질을 인식하는 Goat Polyclonal Antibody로 Western blot에 적합. 합성 펩타이드 면역원 기반으로 제작되었으며, 비결합형 액상 형태로 제공. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide ASGQGPGPPRQE, representing the N-Terminus of the human protein (residues 2–13), according to NP_001179 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1954662 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX22273-PEP).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in a wide variety of cellular activities.
This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to loss of membrane potential and release of cytochrome c.
Additionally, it interacts with the tumor suppressor P53 after exposure to cell stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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