Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI3H7), TrueMAB

Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI3H7), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The ABCB1 gene encodes a membrane-associated protein belonging to the ATP-binding cassette (ABC) transporter superfamily.
These proteins transport various molecules across cellular membranes and are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
ABCB1 is part of the MDR/TAP subfamily, involved in multidrug resistance.
This ATP-dependent efflux pump transports xenobiotic compounds with broad substrate specificity, reducing intracellular drug accumulation and contributing to anticancer drug resistance.
It also functions as a transporter in the blood-brain barrier.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.