Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI3H7), TrueMAB
인간 ABCB1 단백질을 인식하는 마우스 단일클론 항체로 Western blot에 최적화됨. 항원은 인간 ABCB1의 347-710번 아미노산 영역 재조합 단백질. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 다중약제 내성 연구 및 수송 단백질 분석에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI3H7), TrueMAB
Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI3H7), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 347–710 of human ABCB1 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ABCB1 gene encodes a membrane-associated protein belonging to the ATP-binding cassette (ABC) transporter superfamily.
These proteins transport various molecules across cellular membranes and are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
ABCB1 is part of the MDR/TAP subfamily, involved in multidrug resistance.
This ATP-dependent efflux pump transports xenobiotic compounds with broad substrate specificity, reducing intracellular drug accumulation and contributing to anticancer drug resistance.
It also functions as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.