Thermo Fisher Scientific NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), PE
NKG2A/NKG2C/NKG2E를 인식하는 Rat IgG2a 단일클론 항체로, PE 형광표지되어 있습니다. Flow Cytometry에 최적화되어 있으며, 0.2 µg/10⁶ cells로 사용 가능합니다. PBS(pH 7.5) 용액에 보존되며 4°C 암소 보관이 권장됩니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 0.2 µg/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 20d5 |
| Immunogen | Epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.5 |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534430 |
Additional Formats
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family (NKG2 family), a group of transmembrane proteins preferentially expressed in NK cells. This family is characterized by type II membrane orientation and a C-type lectin domain. The protein forms a complex with KLRD1/CD94 and is implicated in the recognition of MHC class I HLA-E molecules in NK cells. The NKG2 gene family forms a receptor gene cluster on chromosome 12, with multiple alternatively spliced transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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