Thermo Fisher Scientific NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), FITC
NKG2A/NKG2C/NKG2E 단백질을 인식하는 FITC 결합 단클론 항체로 Flow Cytometry에 적합. Rat IgG2a/kappa 아이소타입이며, 498/517 nm 형광 특성을 가짐. 4°C 암조건에서 보관하며 연구용으로만 사용.
- 카탈로그번호
- A15416
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µg/1×10⁶ cells
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 20d5 |
| Immunogen | Epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534429 |
Additional Formats
- PE 형식: A15417
- 맞춤 결합 요청: Custom conjugation form
Target Information
Natural killer (NK) cells are lymphocytes that mediate lysis of certain tumor cells and virus-infected cells without prior activation. They also regulate humoral and cell-mediated immunity.
This protein belongs to the killer cell lectin-like receptor family (NKG2 family), a group of transmembrane proteins preferentially expressed in NK cells. These proteins have type II membrane orientation and a C-type lectin domain.
It forms a complex with KLRD1/CD94 and is involved in recognition of MHC class I HLA-E molecules in NK cells. NKG2 family genes form a receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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