Thermo Fisher Scientific c-Fos Polyclonal Antibody
Thermo Fisher Scientific의 c-Fos Polyclonal Antibody는 Western blot과 IHC에 적합한 sheep 유래 IgG 항체입니다. 인간 c-Fos 단백질의 합성 펩타이드로 면역화되었으며, 다양한 종에서 교차 반응성을 보입니다. 연구용으로 세포 신호전달 및 유전자 발현 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human c-Fos protein conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_962058 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute with 100 µL of sterile water.
- OSC00007W can be used with blocking peptide GSC00001P.
- The peptide is homologous in rat and mouse.
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14.
c-Fos heterodimerizes with c-Jun to form the Activator Protein-1 (AP-1) transcription factor, which regulates transcription of several genes involved in cellular signal transduction, proliferation, and differentiation.
c-Fos is phosphorylated by various stimuli, including growth factors and insulin, at multiple sites. The best-known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK, which regulates nuclear localization and transcriptional activity of c-Fos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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