Thermo Fisher Scientific ID4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ID4 protein. Suitable for ICC/IF applications. Purified by antigen affinity chromatography, supplied in liquid form with PBS buffer. Ideal for research on transcription regulation via bHLH family proteins.
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- PA566347
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- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ID4. Recombinant protein control fragment (Product #RP-107030) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662884 |
Product Specific Information
Immunogen sequence:
PLTALNTDPAG AVNKQGDSIL CR
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
ID4 is a transcription factor containing a basic helix-loop-helix (bHLH) motif that regulates expression of tissue-specific genes in mammalian and insect systems. DNA-binding activity of bHLH proteins depends on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit DNA binding and transcriptional activation by heterodimerization with bHLH proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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