Thermo Fisher Scientific SFRS4 Polyclonal Antibody
SFRS4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC(P), ELISA에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SFRS4, amino acids 1–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.
The SR factor family contains one or more RNA recognition motifs (RRM) and an arginine/serine (RS)-rich domain. These proteins are essential for constitutive splicing and regulate alternative splicing by influencing splice site selection.
Most SR proteins, including SC35 and SRp40, are localized in the nucleus, while SF2/ASF, SRp20, and 9G8 shuttle between the nucleus and cytoplasm, contributing to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by hnRNP A/B family proteins, which can alter splice site selection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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