Thermo Fisher Scientific Phospho-MER/SKY (Tyr749, Tyr681) Polyclonal Antibody
Phospho-MER/SKY (Tyr749, Tyr681) 폴리클로날 항체로 Western blot 및 IHC(Paraffin)에 사용 가능. Rabbit IgG 호스트, 액상 형태, 1 mg/mL 농도. 세포 생존, 이동, 분화, 식세포작용 관련 MER/SKY 신호전달 연구에 적합.
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Thermo Fisher Scientific Phospho-MER/SKY (Tyr749, Tyr681) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 749/681 (K-I-Y(p)-S-G) derived from Human MER/SKY |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554416 |
Product Specific Information
- Suggested positive control for Western blot: NIH-3T3 cells
- Suggested positive control for IHC: Human brain tissue
Target Information
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to ligands such as LGALS3, TUB, TULP1, or GAS6.
Regulates physiological processes including:
- Cell survival, migration, and differentiation
- Phagocytosis of apoptotic cells (efferocytosis)
- Platelet aggregation and cytoskeleton reorganization
- Retinal pigment epithelium (RPE) function in rod outer segment phagocytosis
- Inhibition of Toll-like receptor (TLR)-mediated innate immune response via STAT1 activation and SOCS1/SOCS3 induction
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-37808_MERSKY_Q06418-1_Rabbit.svg, PA5-37808_MERSKY_Q12866-1_Rabbit.svg)
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