Thermo Fisher Scientific ASBT Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:300–1:1,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Target Information

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); mutations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.