Thermo Fisher Scientific NRBF2 Monoclonal Antibody (OTI1A2), TrueMAB
Human NRBF2 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 동결건조 형태로 제공되며, PBS buffer(8% trehalose) 보존. 연구용으로만 사용되며, PI3KC3-C1 복합체 관련 오토파지 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human NRBF2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
NRBF2 (nuclear receptor-binding factor 2) modulates transcriptional activation by target nuclear receptors.
It is involved in starvation-induced autophagy through association with PI3K complex I (PI3KC3-C1).
NRBF2 stabilizes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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