Thermo Fisher Scientific TAX1BP1 Polyclonal Antibody
Human TAX1BP1 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:100~1:300 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 내인성 TAX1BP1 단백질을 검출. 연구용으로만 사용 가능.
- 카탈로그번호
- PA550279
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:300
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2635732 |
Product Specific Information
The antibody detects endogenous levels of total TAX1BP1 protein.
Target Information
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3 and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also play a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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